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Percocet (oxycodone / acetaminophen) is a strong narcotic pain -reliever and cough suppressant similar to morphine, codeine, and hydrocodone prescribed to relieve moderate to moderately severe pain.

It is also a prescription medication used to manage moderate to severe pain. It contains a combination of two active ingredients: oxycodone, which is an opioid pain reliever, and acetaminophen, which is a non-opioid pain reliever and fever reducer.

How to Take Oxycodone/Acetaminophen

This form of oxycodone is a pill that can be taken with or without food. You should take the pill whole; if you can’t, contact your care team. Oxycodone/acetaminophen comes in various dosages. The pill is usually taken either as needed for pain or on a regular schedule decided by your care provider. When oxycodone/acetaminophen is swallowed, it gets absorbed by your body. It will begin working to relieve pain in about 15 to 30 minutes, although it reaches its peak effect in 1 hour. It will continue to work for 3 to 6 hours.

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It is important to make sure you are taking the correct amount of medication every time. Before every dose, check that what you are taking matches what you have been prescribed.

Because this medication contains both oxycodone and acetaminophen, an overdose of oxycodone/acetaminophen has the same liver toxicity as an overdose of acetaminophen. There is a maximum amount of acetaminophen that a person can take per day. If someone takes too much oxycodone/acetaminophen, the acetaminophen in it can permanently damage the liver. Be sure to read labels of any other medications you take and do not take any additional acetaminophen. Also, oxycodone/acetaminophen should not be used with alcohol, because the acetaminophen can increase the likelihood that the liver will become damaged.

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This medication can interact with other medications that depress the central nervous system like barbituates (including phenobarbital), tranquilizers (including Haldol®, Librium® and Xanax ®), other narcotics, and general anesthetic. It can also interact with many commonly prescribed medications, as well as herbal supplements. Be sure to tell your healthcare provider about all medications and supplements you take.

DO NOT share this medication or give it to someone else, as severe breathing problems and death can occur.

This medication can cause dizziness, sleepiness, and confusion. You should not drive or operate machinery while taking this medication until you know how it will affect you.